April 19, 2009

Delta 32 mutation

A fascinating news story from Germany about a leukemia patient with AIDS (unrelated to the leukemia) who was given a bone marrow transplant from a donor who had the Delta 32 mutation. When the patient recovered, the AIDS had disappeared as well. Commented Anthony Fauci, director of the National Institute of Allergy and Infections Diseases in the U.S.:

It helps prove the concept that if somehow you can block the expression of CCR5, maybe by gene therapy, you might be able to inhibit the ability of the virus to replicate.

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